17 - Optimizing Antibiotic Dosing in Children: From Monitoring to Management

Thursday, October 12, 2023

8:00 AM – 9:00 AM US ET

Location: 252 AB

All relevant financial disclosures have been mitigated.

Moderator(s)

Manjunath (Amit) Pai, PharmD

Professor and Chair
Clinical Pharmacy, University of Michigan
Ann Arbor, MI, United States
Gauri Rao, PharmD, MS(Pharmacometrics), MS(Computer Engineering) (she/her/hers)

Associate Professor
University of North Carolina Eshelman School of Pharmacy
Chapel Hill, NC, United States

Faculty(s)

Jennifer Goldman, MD, MSCR (she/her/hers)

Professor of Pediatrics
Pediatric Infectious Diseases & Clinical Pharmacology
Children's Mercy Hospital
Kansas City, MO, United States

Slides
Kevin Downes, MD (he/him/his)

Assistant Professor of Pediatrics
Division of Infectious Diseases
Children's Hospital of Philadelphia
Philadelphia, PA, United States

Disclosure(s):

Manjunath (Amit) Pai, PharmD: No financial relationships to disclose

Gauri Rao, PharmD, MS(Pharmacometrics), MS(Computer Engineering): No financial relationships to disclose

CME Credits: Maximum of 1 hours of AMA PRA Category 1 Credit™
MOC Credits: Maximum of 1 hours of MOC Credit
CNE Credits: Maximum of 1 hours of ANCC Credit
ACPE Credits: ACPE 1 knowledge-based contact hours of pharmacy CE
ACPE Number: JA0007082-0000-23-002-L01-P

Co-organized by Consortium of Applied Pharmacometrics (COAP)

Learning Objectives:

At the conclusion of this session, participants will be able to:

recognize key antimicrobial exposure-response and exposure-toxicity relationships;
recognize gaps and opportunities for antibiotic dose optimization in children;
explain the differences between traditional and novel blood sampling methods for therapeutic drug monitoring;
explain how Bayesian dosing approaches can optimize antibiotic dosing with limited information

Presentations:

8:00 AM – 8:30 AM US ET

Therapeutic Drug Monitoring: Moving From Reactive to Proactive
Speaker: Jennifer Goldman, MD, MSCR (she/her/hers) – Children's Mercy Hospital
8:30 AM – 9:00 AM US ET

Practical and Novel Approaches to Therapeutic Drug Monitoring and Antibiotic Dose Optimization
Speaker: Kevin J. Downes, MD (he/him/his) – Children's Hospital of Philadelphia