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George Sakoulas, MD

Adjunct Professor
University of California San Diego School of Medicine
San Diego, CA, United States

Dr. George Sakoulas is an active infectious disease clinician in the Sharp Healthcare System, San Diego, CA, and an Adjunct Professor in the Division of Host-Microbe Systems and Therapeutics, Center for Immunity, Infection and Inflammation at the University of California San Diego School of Medicine. Dr. Sakoulas is also an investigator in the UCSD Health Sciences interdisciplinary research and educational
initiative called the “Collaborative to Halt Antibiotic-ˇResistant Microbes” or CHARM. He has been practicing clinical infectious disease for over 20 years.

Dr. Sakoulas received his undergraduate degree from Columbia University and his medical degree from Harvard Medical School. He completed his clinical training in internal medicine and infectious diseases at the Beth Israel Deaconess Medical Center in Boston.

Through studying the relationships between antimicrobial resistance and bacterial virulence and the interactions between innate host defense and administered antibiotics, Dr. Sakoulas is working towards developing more efficient and effective therapies for common severe infections by utilizing currently available drugs. This includes the repurposing of medications used for other diseases as well as with combination antibiotic therapies aimed at virulence attenuation in addition to conventional direct antibacterial effects. He is also investigating biomarker strategies to risk-stratify patients with infection as a means of directing case-specific therapy, which hopefully will one day help to phase out the 'one size fits all' paradigms common in many treatment algorithms.

Disclosure(s): AbbVie Inc: Advisor/Consultant (Ongoing), Honoraria (Ongoing); Octapharma: Advisor/Consultant (Terminated), Grant/Research Support (Terminated); Paratek Pharmaceuticals: Advisor/Consultant (Ongoing), Honoraria (Ongoing)

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