Director of Infectious Diseases Research
William Beaumont University Hospital, Corewell Health
Matthew Sims, M.D. Ph.D., FACP, FIDSA. – Director of Infectious Diseases Research Corewell Health East
Dr. Sims received his MD and PhD from Stony Brook University with his PhD in Genetics focused on antifungal resistance. He went on to an Internal Medicine residency at Stony Brook and from there to University of Rochester for his Infectious Diseases fellowship followed by an Infectious Diseases research fellowship focused on the impact of antiretroviral resistance mutations on the replication fitness of HIV. He was recruited to start an Infectious Diseases research program for Beaumont Hospital, Royal Oak, in 2006.
He is a board-certified infectious diseases physician, a fellow of both the American College of Physicians and the Infectious Diseases Society of America, and in addition to his research program maintains an active clinical practice. He teaches extensively at OUWB School of Medicine, is course director for the 3rd year Infectious Diseases Interdisciplinary Studies course and holds the academic rank of Professor in the Departments of Internal Medicine and Foundational Medical Studies.
Dr. Sims’ laboratory-based research focuses on resistant and difficult to treat pathogens, the so-called “superbugs” as well as new diagnostics for infections. Dr. Sims runs William Beaumont University Hospital’s Infectious Diseases Clinical Trial Unit and has extensive clinical research experience, serving as PI on over 80 clinical trials of antibiotics and diagnostics. He has been a consultant for design of clinical trials, and a medical monitor for several multi-center trials. He has extensive collaborations and is active with the Antibiotic Resistance Leadership Group. His research has been funded by grants from foundations, the State of Michigan and the federal government and he recently completed an R01 funded by the Agency for Healthcare Research and Quality to study prevention of C. difficile infection.